If you took Super Mario 64, Alone In The Dark, and blended with some H.R. Giger, you might have something like Alice.
Graphics: The technology behind the graphics engine is dated, but the images themselves evoke all the gritty, creepy, and unsettling feelings American McGee intended. The result is an atmosphere of dread, like everything around Alice has been abandoned and poisoned. Even her allies are ragged and sinister in appearance, despite their efforts to help her. Everything about the appearance of the game is great, from the ways the characters move to the details in the clocks. The artists committed to Alice in a labor of love for the macabre.
Sound: The special effects sound are good. The voice acting is appropriate without sounding hokey. Sound effects are muted but match their respective triggering activity. The weapons, like the jacks, sound like jacks. The music is appropriately moody, but nothing spectacular.
Gameplay: Despite its creative environments, characters, and atmosphere, Alice plays like a standard 3d platformer. Alice needs to move about the 3D environment, dispatching enemies with an arsenal of odd weaponry while trying to find the way to the next level. Honestly, there is nothing really special about the gameplay itself you wouldn't find in Ratchet & Clank, Mario 64, or Sonic the Hedgehog. But if you enjoy those games and are into the macabre, you'll love going through the paces with Alice.
I enjoyed Alice. It was creative and moody, while presenting enough of a challenge to keep me highly entertained. There is little replay value once you've gotten through the game, but is worth a play-through if you find it in the bargain bin.