Bioshock completely re-writes th rules for the 1st person genre, creates it's own formula, and perfects it.
The most memorable part of this game is the Little Sisters and Big Daddies. If you have this game you know what I mean, if not, you will soon enough. Little sisterl used to be normal little girls until they were taken underwater to Rapture, genetically enhanced, and posseesed. The best part about them is when you Harvest them, they scream in terror righjt before your eyes.