This game is awesome, but don't be surprised if you piss your pants a couple times.
C2B takes place 11 months after CCO. The main character, Ethan Thomas -- I'm guessing traumatized from his involvement with Serial Killer X in CCO -- has hit rock bottom. He's homeless, living off the bottle, suffering sudden (and often violent) hallucinations, being more violent and more darker. And guess what? he's being called back into action to investigate a murder commited against his mentor, Maicolm Van Horn. That's right, you get to go back to beating the s**t out of crazy psychopaths. Bloodshot has some moments that will probably have you screaming and checking your pants simultaneously (you may want to keep that light on). Want more blood? You got it! Bloodshot has some graphic (but memorable) finishing moves that will either (1. Have you laughing and saying "I want to do that again!" (2. In awe of what just happened. (3. "WTF?!" (4. Sleeping with the TV on the Weather Channel. Maybe you can create moments of your own. The basic hand-to-hand combat system has fine-tuned; now you fight with your fists, and string together some interesting combos. Anyways, take care in playing this game. Warning: this game is DEFINITELY not for the squeamish.
If you can ignore all the blood and guts, Bloodshot is a definite must have. Superb graphics and gameplay -- strung together with some awe-aspiring moments -- really sets Bloodshot apart from the rest of the survival horror crowd. Keep a light on, have someone with you, and maybe bring an extra pair of pants and boxers, and enjoy Bloodshot to your hearts content (just don't get a heart attack from what you see).