In my opinion, the 10 best games to start off with would be (in no particular order);
Super Mario 64 DS (always a classic, and this remake is even better, with a lot more to do than the original)
Mario Kart DS(greatest racing series ever, and the wifi component rules)
Legend of Zelda: Phantom Hourglass (unbelievable graphics and gameplay)
Clubhouse Games (perfect multi-player game)
Starfox Command (not quite the same as the originals, but still a great game)
Final Fantasy III (fantastic remake of a never-released-in-North-America game)
Pokemon Diamond/Pearl (good, full RPG)
Castlevania Dawn of Sorrow (great addition to the series)
Animal Crossing (a fun little diversion, perfect game for playing few minutes here and there)
Konami Arcade Classics (nice collection of old-school games)
Another game to consider, and has been listed before, is Metroid Prime Hunters, great game for Wifi battle.
Hope this list helps!!
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