They have 4x4GB for desktops too
http://newgskill.web-bi.net/bbs/view.php?id=g_ddr2&page=1&sn1=&divpage=1&sn=off&ss=on&sc=on&select_arrange=headnum&desc=asc&no=123
4x2GB is totally usable for Windows Vista. Vista will use about as much RAM as you throw at it.
http://www.tomshardware.com/reviews/vista-workshop,1775.html
So I am sure 4x4GB would be fine. RAM is so cheap, you better be putting at least 4GB in for new systems. And I would suggest 2x2GB not 4x1GB so you can upgrade to 4x2GB later. Now if you have XP, then 8GB isn't going to made as much of a difference, but 4GB is starting to be standard now.
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