I would recommend you to not. It gets you accustomed to the events and characters before Mass Effect 2. A lot of those characters make a return in the sequel, and certain events are referenced. Mass Effect 2 improves in a lot of areas, though, so some things in the first one might not seem as 'fresh'.
If you really don't wanna play the first one, maybe you should import one of the saved games avaialbe to everyone on the web. It decides if your Shepard was good/bad/neutral in ME 1, as well as some other important decisions such as romance options.
BioWare should really add some form of, uh, customization options in their sequels that are affected by decisions made in previous games, instead of just relying on saved games. It would be easier and I feel that the people who do not play previous games are missing out on certain parts of the game. Plus you have to play the first game again if you want to import OTHER changes.
I hear that's changing to SOME extent in Dragon Age 2, though.
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