Well, i have the exact same question as the OP. i'm playing the beta at 1280x1024 everything on high but the shadows wich are set to medium, also, it's playing with a mod from the official beta forums to all of the .cfg files in the installation folder, an it's looking impressive, even better than w/o the mod, also it's running somewhat smoother (even though my 320 is paired with an x2 4800+). Of Course, it's still running on dx9 and no AA, but i'm happy that a simple mod to the config files makes such a good improvement (at least for me), because i'm thinking crytek will make it run pretty good when it retails.
Still, all this apply to dx9, and we really don't have any idea how will it run on dx10 for now, the only thing i can tell you is that in my opinion the 320 will run it pretty good at 1280 and 1440 in dx9 (i'm 80% sure though). and yes, i'm scared too because i want to play this game in dx10 at least 1024x786 2xAA high/very high settings....
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