Im not positive but i think if you buy OEM you cant call in to micrososft for tech support. Your operating system will also be tied to the motherboard you had in your system when you installed vista. If you swap motherboards in the future you cant use the same OEM disc for your new system.
Actually the only thing that I know of thats different between the retail and the OEM copy is that the OEM version is either 32 or 64 bit whereas the retail copy has both. Everything else is the same.
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