Folding@Home on a Personal Level.

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KaptainKernal

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#1 KaptainKernal
Member since 2006 • 1787 Posts

Folding@Home is amazing. I dedicate to do it every night and most of the day while I am at school. My father died of cancer so this project is personal to me. Every night and most of the day. Even if not directly cancer, because it does reseach on other desease. Not magic but it Helps. Just a small push into gettting closer. Just a small helping hand.

 

While not some magic that will cure everything it is important and needs to be continued whie small. Again it Helps.

 

And being around chemists in my family for many years I know alot about the impications of this program. My cosin was one of the main reseachers in dicovering how protiens like p53 stop poduction and how it effects p21 and vice versa.

 

 

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jackle2071

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#2 jackle2071
Member since 2004 • 5477 Posts
so did my grandfather. thats why it was the first thing i did when i installed 1.6 i have no problem leaving it on for the rest of the night!
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longhorn7

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#3 longhorn7
Member since 2007 • 4637 Posts

Folding@Home is amazing. I dedicate to do it every night and most of the day while I am at school. My father died of cancer so this project is personal to me. Every night and most of the day.

PS:

WOW I am really suprised in how cool remote play it. I can control my PS3 from my PSP! I does everything from pictures to music to videos. I even sent daveman3 a message over PSN using remote play!! IT ROCKS! you can even access the PS Store!!

KaptainKernal
i agree my girlfriend of almost 2 years that i have been good friends with since 7th grade is going through chemotherapy its a tough thing to see i cant imagine what she feels sometimes. im glad to be part of something that can help people especially the ones i love
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BViking78

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#4 BViking78
Member since 2005 • 390 Posts
Since my PC is 24/7 I don't think I'll have any problems to do the same with my PS3 (my Wii is connected 24/7 too)... Anyway my mother, luckly, survived so it's kinda personal too... :)
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NextGenNow

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#5 NextGenNow
Member since 2007 • 2622 Posts
Dude...I won't lie I got really teary eyed thinking someone out there will have a chance at life because I'm running a program to help them. PS3 has won in my book just cause of this alone.
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KaptainKernal

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#6 KaptainKernal
Member since 2006 • 1787 Posts
Exactly
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mikeslemonade

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#7 mikeslemonade
Member since 2006 • 3624 Posts
Cancer will physically effect half us in the U.S. in some point in our lifetime.  In other words have of us will have some sort of cancer. 
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NextGenNow

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#8 NextGenNow
Member since 2007 • 2622 Posts
Cancer is a disgusting disease that ravages our planet daily and it has no limits. One cannot imagine the feeling I had of watching my grandpa crack jokes, then watching him get weaker, and weaker, until finally he was bed ridden and could barely keep his eyes open. When my grandma came to my house and told our family in person he passed away I was devastated....that man was like my father...Carrying his coffin only 8 months after laughing with him tore me up. The hardest part is that only 2 months later I went to Ft. Benning 1/50th ITB (for you cats that know what it is you can see my picture on my myspace page.) I wanted my grandpa to be the one next to me in my uniform but he died before I could graduate...running this program brings me a great level of peace...I'm sure there are tons of ou guys who know how terrible this disease really is...this is by far one of the most amazing things I've ever seen ANY mainstream company do. It means a lot to me and I thank Sony for doing this...thanks TC I didn't really think anyone in here cared enough to post about this.
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longhorn7

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#9 longhorn7
Member since 2007 • 4637 Posts
Cancer is a disgusting disease that ravages our planet daily and it has no limits. One cannot imagine the feeling I had of watching my grandpa crack jokes, then watching him get weaker, and weaker, until finally he was bed ridden and could barely keep his eyes open. When my grandma came to my house and told our family in person he passed away I was devastated....that man was like my father...Carrying his coffin only 8 months after laughing with him tore me up. The hardest part is that only 2 months later I went to Ft. Benning 1/50th ITB (for you cats that know what it is you can see my picture on my myspace page.) I wanted my grandpa to be the one next to me in my uniform but he died before I could graduate...running this program brings me a great level of peace...I'm sure there are tons of ou guys who know how terrible this disease really is...this is by far one of the most amazing things I've ever seen ANY mainstream company do. It means a lot to me and I thank Sony for doing this...thanks TC I didn't really think anyone in here cared enough to post about this.NextGenNow
hooah, i have pt in 45 minutes :lol:
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KaptainKernal

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#10 KaptainKernal
Member since 2006 • 1787 Posts
Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.
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longhorn7

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#11 longhorn7
Member since 2007 • 4637 Posts
Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.KaptainKernal
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways
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NextGenNow

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#12 NextGenNow
Member since 2007 • 2622 Posts
[QUOTE="NextGenNow"]Cancer is a disgusting disease that ravages our planet daily and it has no limits. One cannot imagine the feeling I had of watching my grandpa crack jokes, then watching him get weaker, and weaker, until finally he was bed ridden and could barely keep his eyes open. When my grandma came to my house and told our family in person he passed away I was devastated....that man was like my father...Carrying his coffin only 8 months after laughing with him tore me up. The hardest part is that only 2 months later I went to Ft. Benning 1/50th ITB (for you cats that know what it is you can see my picture on my myspace page.) I wanted my grandpa to be the one next to me in my uniform but he died before I could graduate...running this program brings me a great level of peace...I'm sure there are tons of ou guys who know how terrible this disease really is...this is by far one of the most amazing things I've ever seen ANY mainstream company do. It means a lot to me and I thank Sony for doing this...thanks TC I didn't really think anyone in here cared enough to post about this.longhorn7
hooah, i have pt in 45 minutes :lol:

Hooah! gotta love the morning PT! I'm an 11 Bravo what MOS are you? *prays he's not a CAV scout* lol!
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NextGenNow

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#13 NextGenNow
Member since 2007 • 2622 Posts
Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.KaptainKernal
AMEN!!! It is a filthy disease right up there with AIDS....I stand with ya man!!
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mztazmz

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#14 mztazmz
Member since 2003 • 1405 Posts
I haven't personally lost anyone to cancer, but reading your posts seriously got me feeling even better about how we'll be able to help with our PS3's. If our contribution saves just one life, it will be the best $600 I ever spent:)
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NextGenNow

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#15 NextGenNow
Member since 2007 • 2622 Posts
[QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.longhorn7
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!
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jackle2071

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#16 jackle2071
Member since 2004 • 5477 Posts
it seems like this is also a nice way of bring people togeather! it also shows that there is still alot of wonderfull people out there in the wrold!
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NextGenNow

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#17 NextGenNow
Member since 2007 • 2622 Posts
I haven't personally lost anyone to cancer, but reading your posts seriously got me feeling even better about how we'll be able to help with our PS3's. If our contribution saves just one life, it will be the best $600 I ever spent:)mztazmz
It is money well spent. Hearin all you guys talk about how it has affected you reminds me of another reason why I like games...it's an ugly world we live in....it can be pretty but a whole bunch of it is really ugly...gaming is a nice escape....now we have a way of escaping it while helping it! 1.60 Best. System Update. Ever. :)
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longhorn7

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#18 longhorn7
Member since 2007 • 4637 Posts
[QUOTE="longhorn7"][QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.NextGenNow
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!

thanks man, dont worry im no cav scout lol even worse im a cadet right now lol i signed up for the army reserve and they scooped me up right away for the full 4 year scholarship here to the university of alabama
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NextGenNow

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#19 NextGenNow
Member since 2007 • 2622 Posts
[QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.longhorn7
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!

thanks man, dont worry im no cav scout lol even worse im a cadet right now lol i signed up for the army reserve and they scooped me up right away for the full 4 year scholarship here to the university of alabama

ahhh yes Butter Bars in training! I know some cool ass cadets, they are in our unit learning the ropes of the Infantry Officers. Trust me it's not as bad as CAV scouts lol little cross saber crap LOL! Yeah bro it's tight you are startin as like an MS2? I don;t knwo a whole lot about cadet training other than it consists of leadership skills and what not. Good stuff though, never really met one that wasn;t polite. A bit diffrent from being an enlisted Infantryman lol where every other word starts with F. :lol:
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longhorn7

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#20 longhorn7
Member since 2007 • 4637 Posts
[QUOTE="longhorn7"][QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.NextGenNow
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!

thanks man, dont worry im no cav scout lol even worse im a cadet right now lol i signed up for the army reserve and they scooped me up right away for the full 4 year scholarship here to the university of alabama

ahhh yes Butter Bars in training! I know some cool ass cadets, they are in our unit learning the ropes of the Infantry Officers. Trust me it's not as bad as CAV scouts lol little cross saber crap LOL! Yeah bro it's tight you are startin as like an MS2? I don;t knwo a whole lot about cadet training other than it consists of leadership skills and what not. Good stuff though, never really met one that wasn;t polite. A bit diffrent from being an enlisted Infantryman lol where every other word starts with F. :lol:

lol my problem is i fit in much more with the enlisted infantrymen than the nice and polite officers in training. im starting out as an ms1 because they offered me the scholarship before basic, but had i gone to basic first i would have gone in as ms2 i think. theres a lot of backstabbers in it because they are already tryin to play the politics game. its pretty bad really lol i might end up just sayin screw it and enlisting if it gets too much worse lol but yeah im prolly gonna be an mp and then after that just be tuscaloosa pd and after all my crap is straight move back to texas and become walker texas ranger's successor lol
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NextGenNow

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#21 NextGenNow
Member since 2007 • 2622 Posts
[QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.longhorn7
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!

thanks man, dont worry im no cav scout lol even worse im a cadet right now lol i signed up for the army reserve and they scooped me up right away for the full 4 year scholarship here to the university of alabama

ahhh yes Butter Bars in training! I know some cool ass cadets, they are in our unit learning the ropes of the Infantry Officers. Trust me it's not as bad as CAV scouts lol little cross saber crap LOL! Yeah bro it's tight you are startin as like an MS2? I don;t knwo a whole lot about cadet training other than it consists of leadership skills and what not. Good stuff though, never really met one that wasn;t polite. A bit diffrent from being an enlisted Infantryman lol where every other word starts with F. :lol:

lol my problem is i fit in much more with the enlisted infantrymen than the nice and polite officers in training. im starting out as an ms1 because they offered me the scholarship before basic, but had i gone to basic first i would have gone in as ms2 i think. theres a lot of backstabbers in it because they are already tryin to play the politics game. its pretty bad really lol i might end up just sayin screw it and enlisting if it gets too much worse lol but yeah im prolly gonna be an mp and then after that just be tuscaloosa pd and after all my crap is straight move back to texas and become walker texas ranger's successor lol

Yeah dude it's a tough line those guys walk. I couldn't deal with all the political BS. That's why I went Infantry straight up. I got offered an entry as MS2 cuz I went to Benning beforehand but I said nahhh. If you do go enlisted you'll like it but ya better be ready to be at the botom of a whole new heap man lol NCO's can be a pain in the A$$! When I finally made Spc. they got chill but dang bro being a Private ANYTHING sucks :lol: 
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Ice-Cube

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#22 Ice-Cube
Member since 2003 • 2450 Posts
Wow..just listening to your stories really got to me man. Using this program does make me feel like i'm helping in some sort of way and I truly hope something good comes out of this one day. Also Gaming is my time to escape some of the harshest things in the world, just like you stated in your post. It's just my way to relax. Great Topic.
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longhorn7

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#23 longhorn7
Member since 2007 • 4637 Posts
[QUOTE="longhorn7"][QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="NextGenNow"][QUOTE="longhorn7"][QUOTE="KaptainKernal"]Cancer robbed me of half my childhood and my dad's life. It is really a terrible desease. Pure Evil in many respects. I hope this small endevor can help rid the world of it, once and for all.NextGenNow
yeah watching the girl i would love to marry slowly battle it is a tough thing, and im glad we can do something to help people like our loved ones out, even if it is in the smallest of ways

damn man....I feel for ya....that's horrible...I'll keep my PS3 runnin for her!

thanks man, dont worry im no cav scout lol even worse im a cadet right now lol i signed up for the army reserve and they scooped me up right away for the full 4 year scholarship here to the university of alabama

ahhh yes Butter Bars in training! I know some cool ass cadets, they are in our unit learning the ropes of the Infantry Officers. Trust me it's not as bad as CAV scouts lol little cross saber crap LOL! Yeah bro it's tight you are startin as like an MS2? I don;t knwo a whole lot about cadet training other than it consists of leadership skills and what not. Good stuff though, never really met one that wasn;t polite. A bit diffrent from being an enlisted Infantryman lol where every other word starts with F. :lol:

lol my problem is i fit in much more with the enlisted infantrymen than the nice and polite officers in training. im starting out as an ms1 because they offered me the scholarship before basic, but had i gone to basic first i would have gone in as ms2 i think. theres a lot of backstabbers in it because they are already tryin to play the politics game. its pretty bad really lol i might end up just sayin screw it and enlisting if it gets too much worse lol but yeah im prolly gonna be an mp and then after that just be tuscaloosa pd and after all my crap is straight move back to texas and become walker texas ranger's successor lol

Yeah dude it's a tough line those guys walk. I couldn't deal with all the political BS. That's why I went Infantry straight up. I got offered an entry as MS2 cuz I went to Benning beforehand but I said nahhh. If you do go enlisted you'll like it but ya better be ready to be at the botom of a whole new heap man lol NCO's can be a pain in the A$$! When I finally made Spc. they got chill but dang bro being a Private ANYTHING sucks :lol:

Haha yeah thats what i hear, my grandfather is a Command Sergeant Major(Ret.) and he used to screw with folks so bad. He was a drill instructor for a while there after vietnam and whew lol. But yeah the politics thing definately is not for me. Im too loyal to backstab and i have too short of a temper to let backstabbers get by without a nice punch to the jaw lol.
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NextGenNow

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#24 NextGenNow
Member since 2007 • 2622 Posts
Wow..just listening to your stories really got to me man. Using this program does make me feel like i'm helping in some sort of way and I truly hope something good comes out of this one day. Also Gaming is my time to escape some of the harshest things in the world, just like you stated in your post. It's just my way to relax. Great Topic.Ice-Cube
Most def. And for some it hits harder than others...the TC lost a direct family member to it. Only thing I could compare that to would be my ma. So sad to watch people pass away from it....plus it always tends to find good people for some reason....rarely hear about murderers or rapist gettin cancer...wish the disease was selective but sadly it targets us all.
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Wii26

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#25 Wii26
Member since 2006 • 4661 Posts
Out of curiousity, how does this work exactly?
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amourkiss

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#26 amourkiss
Member since 2003 • 1751 Posts

let's give heart when we are available

power of PS3 united

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Dust24311

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#27 Dust24311
Member since 2004 • 1215 Posts

I'm a scientist at Southern Research Institute in Maryland, USA. 

 

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences.  That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

 

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry.  While this may seem impressive, none of this information has led to clinical research of any significance.

 

Just wanted to get the word out.  This program was made to predict protein folding and that is the ONLY thing it does.  It does not magically cure cancer. 

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Wii26

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#28 Wii26
Member since 2006 • 4661 Posts

I'm a scientist at Southern Research Institute in Maryland, USA.

 

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences. That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

 

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry. While this may seem impressive, none of this information has led to clinical research of any significance.

 

Just wanted to get the word out. This program was made to predict protein folding and that is the ONLY thing it does. It does not magically cure cancer.

Dust24311

 
It's not only for that but folding@home binds consoles and computers alike to apparently form some super computer to help simulate real life problems. We know it's not going to create a magical cure, but it's helping scientists figure out problems and so forth. It's not only to educate but to help. I think you missed that whole bit. 

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firestorm91

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#29 firestorm91
Member since 2006 • 4538 Posts
Cancer has affected my grandmother so I'm going to help in some way. :D
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Wii26

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#30 Wii26
Member since 2006 • 4661 Posts

Furthermore mr. Dust24311, it actually has done some good. They have found results on peptids in nanotubes, results on p53, and has even led to computational drug design. Shazaam! 

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Dust24311

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#31 Dust24311
Member since 2004 • 1215 Posts
[QUOTE="Dust24311"]

I'm a scientist at Southern Research Institute in Maryland, USA.

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences. That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry. While this may seem impressive, none of this information has led to clinical research of any significance.

Just wanted to get the word out. This program was made to predict protein folding and that is the ONLY thing it does. It does not magically cure cancer.

Wii26


It's not only for that but folding@home binds consoles and computers alike to apparently form some super computer to help simulate real life problems. We know it's not going to create a magical cure, but it's helping scientists figure out problems and so forth. It's not only to educate but to help. I think you missed that whole bit.

WRONG, it does not "simulate real life problems". It takes a protein of interest and folds it based upon amino acid folding rules. The program assigns batches (work units) to clusters of processors and returns the information to Stanford. It is simply a scientific tool, not a magical "real life problem" solver. You must understand that it is my duty as a scientist to inform people that they are using a tool so that they don't get disappointed when FAH doesn't cure cancer later this year. I'm really trying to be nice here, but when people are talking about empirical scientific evidence, you can only go with the facts. :)
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animation_imp

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#32 animation_imp
Member since 2005 • 155 Posts
I want to react on this... The above post is true, however, do not be discouraged because of it. The research is indeed not specifically aimed at cancer research and it probably won't yield any practical information in the near future. Still it's very important and I hope everyone keeps running the program. Proteïns are what makes the world go round sort of speak, and a clear understanding of proteïn-folding and where it can go wrong is key to understanding some of the mechanisms behind cancer, Alzheimer, Parkinson, etc... This research is important and you can help using your favourite gaming console. And I find it a bit childish of Dust24311 to put this down. By the way, I have no ties with Sony or the Stanford Universities and I'm a Master in Biology, got my degree at the University of Ghent in Belgium. I know what I'm talking about.
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Dust24311

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#33 Dust24311
Member since 2004 • 1215 Posts

Furthermore mr. Dust24311, it actually has done some good. They have found results on peptids in nanotubes, results on p53, and has even led to computational drug design. Shazaam!

Wii26
I agree that it is a useful tool. But what has it done? Lets examine the evidence: It took nanotubes with known chemical structure (down to the atom) and simply found where it could fold. It took p53, which has been COMPLETELY MAPPED OUT to the amino acid (we also know the genome and the nucleotide sequence, promoter regions, etc) and found out where it could fold. Oh, and drug design... it can take something like acetaminophen and find rotational angles around chiral carbons. My point: it is a tool of less-than-impressive scientific value.
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jackle2071

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#34 jackle2071
Member since 2004 • 5477 Posts
[QUOTE="Wii26"][QUOTE="Dust24311"]

I'm a scientist at Southern Research Institute in Maryland, USA.

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences. That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry. While this may seem impressive, none of this information has led to clinical research of any significance.

Just wanted to get the word out. This program was made to predict protein folding and that is the ONLY thing it does. It does not magically cure cancer.

Dust24311


It's not only for that but folding@home binds consoles and computers alike to apparently form some super computer to help simulate real life problems. We know it's not going to create a magical cure, but it's helping scientists figure out problems and so forth. It's not only to educate but to help. I think you missed that whole bit.

WRONG, it does not "simulate real life problems". It takes a protein of interest and folds it based upon amino acid folding rules. The program assigns batches (work units) to clusters of processors and returns the information to Stanford. It is simply a scientific tool, not a magical "real life problem" solver. You must understand that it is my duty as a scientist to inform people that they are using a tool so that they don't get disappointed when FAH doesn't cure cancer later this year. I'm really trying to be nice here, but when people are talking about empirical scientific evidence, you can only go with the facts. :)

yes but the over all point is that it is doing somthing good! rite!? but you are rite to clear up all the miss information so people understand, but i could not help feeling your post might come off as a bit cold to some people. its not your fault at all so im not trying to pick on you just saying.
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Dust24311

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#35 Dust24311
Member since 2004 • 1215 Posts
[QUOTE="animation_imp"]I want to react on this... The above post is true, however, do not be discouraged because of it. The research is indeed not specifically aimed at cancer research and it probably won't yield any practical information in the near future. Still it's very important and I hope everyone keeps running the program. Proteïns are what makes the world go round sort of speak, and a clear understanding of proteïn-folding and where it can go wrong is key to understanding some of the mechanisms behind cancer, Alzheimer, Parkinson, etc... This research is important and you can help using your favourite gaming console. And I find it a bit childish of Dust24311 to put this down. By the way, I have no ties with Sony or the Stanford Universities and I'm a Master in Biology, got my degree at the University of Ghent in Belgium. I know what I'm talking about.

Childish to tell posters that say "this program will cure cancer" how this program ACTUALLY WORKS! I don't call that childish, I call it RESPONSIBLE.
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Wii26

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#36 Wii26
Member since 2006 • 4661 Posts
[QUOTE="Wii26"][QUOTE="Dust24311"]

I'm a scientist at Southern Research Institute in Maryland, USA.

 

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences. That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

 

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry. While this may seem impressive, none of this information has led to clinical research of any significance.

 

Just wanted to get the word out. This program was made to predict protein folding and that is the ONLY thing it does. It does not magically cure cancer.

Dust24311


It's not only for that but folding@home binds consoles and computers alike to apparently form some super computer to help simulate real life problems. We know it's not going to create a magical cure, but it's helping scientists figure out problems and so forth. It's not only to educate but to help. I think you missed that whole bit.

WRONG, it does not "simulate real life problems". It takes a protein of interest and folds it based upon amino acid folding rules. The program assigns batches (work units) to clusters of processors and returns the information to Stanford. It is simply a scientific tool, not a magical "real life problem" solver. You must understand that it is my duty as a scientist to inform people that they are using a tool so that they don't get disappointed when FAH doesn't cure cancer later this year. I'm really trying to be nice here, but when people are talking about empirical scientific evidence, you can only go with the facts. :)

Have you not read up on this? If you have then you would know I am not wrong.

"You can help by simply running a piece of software. Folding@Home is a distributed computing project -- people from through out the world download and run software to band together to make one of the largest supercomputers in the world. Every computer makes the project closer to our goals.

Folding@Home uses novel computational methods coupled to distributed computing, to simulate problems thousands to millions of times more challenging than previously achieved."

 

Folding@Home Main Page

My apologies not real life problems but problems thousand to million times more challenging. Craziness isn't it? I never said it was a magical cure nor did anyone else. You missed the whole part about people linking together to help increase research. It's not suppose to be a cure. You completely missed the point of the entire program and what people are doing. It is suppose to HELP with cancer research. Everyone knows it's not a cure. Just because you're a scientist doesn't mean anything. It doesn't take one to realize this isn't meant to cure but instead HELP. Sorry I can't emphasize enough how this is suppose to help and not cure. Everyone knows that but you come running here like you can contribute something when all you have done is been a downer. You aren't helping at all. You're just showing that you can brag about scientific knowledge and claim that your a scientist. Whoopie doo who cares?

And did I say it was a real life problem solver? Maybe you should indulge yourself into some reading no? The problem here seems to be more that you can't read what people post so you take it in your hands to educate us. The concept of  folding@home is to simulate problems thousand to millions more challenging then real life and previously achieved. That's the point of it! Yes to fold proteins but to help simulate! Go read up on it. It's not that hard to type it into google. 

The thing that's twitching me right now is that just because we don't have scientific degrees, we know nothing. We know that it won't cure cancer later this year. You state something so obvious that even a child would know. My 14 year old brother understands this simple concept. Sorry but you have contributed next to nothing in this thread except to show that you're arrogant. 

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animation_imp

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#37 animation_imp
Member since 2005 • 155 Posts

[QUOTE="animation_imp"]I want to react on this... The above post is true, however, do not be discouraged because of it. The research is indeed not specifically aimed at cancer research and it probably won't yield any practical information in the near future. Still it's very important and I hope everyone keeps running the program. Proteïns are what makes the world go round sort of speak, and a clear understanding of proteïn-folding and where it can go wrong is key to understanding some of the mechanisms behind cancer, Alzheimer, Parkinson, etc... This research is important and you can help using your favourite gaming console. And I find it a bit childish of Dust24311 to put this down. By the way, I have no ties with Sony or the Stanford Universities and I'm a Master in Biology, got my degree at the University of Ghent in Belgium. I know what I'm talking about.Dust24311
Childish to tell posters that say "this program will cure cancer" how this program ACTUALLY WORKS! I don't call that childish, I call it RESPONSIBLE.

No it isn't responsible, these people are helping and this program has potential, albeit being in an early stage.

If people feel better using this program and get a sence of closure in the example of the posters in this thread, then I think it's not your job to burst their bubble. I find it very immature and painfull for the people with good will who want to contribute to a potentially immense community of normal every-day people helping out in scientific research.

Another point I'de like to make is people need it to be explained so everyone can understand, If one were to explain what the program actually does it would have only a minimal following. Explaining it using examples like cancer and Alzheimer, makes it much easier to understand and so more people will join in. Does this negatively influence you personnaly, no, so leave them be. Put your energy into something else, there's a lot more semi-scientifical BS going around...

You can show how greenpeace uses false numbers and outdated research techniques to get nice graphs so they can get more money from the masses. You can show people that All Gore's "Inconvenient thruth" is way overblown and there's lot's of scientific research to back you up... You can inform people on the fact that global warming has very probably nothing to do with human CO2 emmisions... etc... There are enough semi-scientific BS causes for you to lay in the open, so leave this harmless, free (except for the electricity you spend of course) and potentially great project alone.

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Wii26

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#38 Wii26
Member since 2006 • 4661 Posts
[QUOTE="Wii26"]

Furthermore mr. Dust24311, it actually has done some good. They have found results on peptids in nanotubes, results on p53, and has even led to computational drug design. Shazaam!

Dust24311

I agree that it is a useful tool. But what has it done? Lets examine the evidence: It took nanotubes with known chemical structure (down to the atom) and simply found where it could fold. It took p53, which has been COMPLETELY MAPPED OUT to the amino acid (we also know the genome and the nucleotide sequence, promoter regions, etc) and found out where it could fold. Oh, and drug design... it can take something like acetaminophen and find rotational angles around chiral carbons. My point: it is a tool of less-than-impressive scientific value.

Yes but when proteins don't fold properly they can lead to several diseases. You're right, it could be one of the reasosn for Alzheimer's but who cares right? No significance. 

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ilikemilk007

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#39 ilikemilk007
Member since 2004 • 138 Posts
[QUOTE="Dust24311"][QUOTE="Wii26"][QUOTE="Dust24311"]

I'm a scientist at Southern Research Institute in Maryland, USA.

 

I think it's important for me to inform everyone that Folding at Home is not for cancer research, but simply to understand how proteins fold based upon their amino acid sequences. That said, this program is limited by the programming and the application of the scientists at Stanford Universities Chemistry department.

 

The program has led to approximatelly 50 scientific research articles being published on the subject of medicinal chemistry. While this may seem impressive, none of this information has led to clinical research of any significance.

 

Just wanted to get the word out. This program was made to predict protein folding and that is the ONLY thing it does. It does not magically cure cancer.

Wii26


It's not only for that but folding@home binds consoles and computers alike to apparently form some super computer to help simulate real life problems. We know it's not going to create a magical cure, but it's helping scientists figure out problems and so forth. It's not only to educate but to help. I think you missed that whole bit.

WRONG, it does not "simulate real life problems". It takes a protein of interest and folds it based upon amino acid folding rules. The program assigns batches (work units) to clusters of processors and returns the information to Stanford. It is simply a scientific tool, not a magical "real life problem" solver. You must understand that it is my duty as a scientist to inform people that they are using a tool so that they don't get disappointed when FAH doesn't cure cancer later this year. I'm really trying to be nice here, but when people are talking about empirical scientific evidence, you can only go with the facts. :)

Have you not read up on this? If you have then you would know I am not wrong.

"You can help by simply running a piece of software. Folding@Home is a distributed computing project -- people from through out the world download and run software to band together to make one of the largest supercomputers in the world. Every computer makes the project closer to our goals.

Folding@Home uses novel computational methods coupled to distributed computing, to simulate problems thousands to millions of times more challenging than previously achieved."

 

Folding@Home Main Page

My apologies not real life problems but problems thousand to million times more challenging. Craziness isn't it? I never said it was a magical cure nor did anyone else. You missed the whole part about people linking together to help increase research. It's not suppose to be a cure. You completely missed the point of the entire program and what people are doing. It is suppose to HELP with cancer research. Everyone knows it's not a cure. Just because you're a scientist doesn't mean anything. It doesn't take one to realize this isn't meant to cure but instead HELP. Sorry I can't emphasize enough how this is suppose to help and not cure. Everyone knows that but you come running here like you can contribute something when all you have done is been a downer. You aren't helping at all. You're just showing that you can brag about scientific knowledge and claim that your a scientist. Whoopie doo who cares?

And did I say it was a real life problem solver? Maybe you should indulge yourself into some reading no? The problem here seems to be more that you can't read what people post so you take it in your hands to educate us. The concept of  folding@home is to simulate problems thousand to millions more challenging then real life and previously achieved. That's the point of it! Yes to fold proteins but to help simulate! Go read up on it. It's not that hard to type it into google. 

The thing that's twitching me right now is that just because we don't have scientific degrees, we know nothing. We know that it won't cure cancer later this year. You state something so obvious that even a child would know. My 14 year old brother understands this simple concept. Sorry but you have contributed next to nothing in this thread except to show that you're arrogant. 

This is a very innteresting thread, I think I may just download this tonight. Its always nice to help in a way that I can.
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mcxps3

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#40 mcxps3
Member since 2007 • 659 Posts
my grandma died of cancer. i also have known acouple of kids with it. i will always keep it on no matter what it costs to keep the system on
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Dust24311

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#41 Dust24311
Member since 2004 • 1215 Posts
After reading all of these responses, I must say that this last bout of discussion has, indeed, brought a lot information on FAH to this forum. Hopefully people read and understand this program in it's context. The problem with forums is that someone takes a stance, and defends it to the death. If you reread my posts, I never blast the program. I describe it's function as I will describe any other tool in science. I describe how it predicts protein folding to inform users, not intimidate them. It's amazing how I simply describe a program's EMPIRICAL function, and I am met with EMOTION (I am called arrogant and childish). I truly hope everyone downloads the program and uses it, and if I help people use the program WITHOUT FALSE PRETENSES then so be it. I must get back to work. Enjoy the day everyone.
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jackle2071

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#42 jackle2071
Member since 2004 • 5477 Posts
you see we can all play nice! we can all agree thats it is for somthing good and not just a waste of time! i just finshed my first Folding Project. it took 3 or 4 hours but hay!
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Trek5200

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#43 Trek5200
Member since 2007 • 599 Posts

I lost my mother when I was 22 and my father 10 months later.  My mother was given two years and lasted two months, my father was diagnosed and lasted 8 days.

I for one will be using the folding program constantly and it disgusts me everytime I hear some selfish selfcentered moron discuss the reasons why they won't. 

To all of you who are using the Folding program CONGRATULATIONS!!  You are a better person because of it!  Imagine the pleasure we could all experience if down the road they find some breakthrough information because WE got together and did something selfless and intelligent.

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danjammer69

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#44 danjammer69
Member since 2004 • 4331 Posts

I will do my part in this experiment. It means a bit to me since my father is currently in remission for bladder cancer. He got in a bad industrial chemical accident whilst working for Con-Ed in NY City. This led to his cancer.

Help give others a fighting chance;

Do your part, Download FOLDING @HOME today

 

 

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sabru8

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#45 sabru8
Member since 2003 • 4144 Posts
I lost an uncle due to complications with cancer.
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#46 Pixelgen
Member since 2006 • 633 Posts

On the one hand I can see the benefits of running the program, but I'm a little worried about leaving my PS3 on for too long. I pick up my PS3 tomorrow and I don't want to burn it out within months. In the end I think I will run the program 4/6 hours a week, but I have read on forums of people planning on running the program overnights or during work hours. If you add in the GamePlay hours and Blu-Ray moments, I think the PS3 is going to be running to hot...  :)

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Ice-Cube

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#47 Ice-Cube
Member since 2003 • 2450 Posts

On the one hand I can see the benefits of running the program, but I'm a little worried about leaving my PS3 on for too long. I pick up my PS3 tomorrow and I don't want to burn it out within months. In the end I think I will run the program 4/6 hours a week, but I have read on forums of people planning on running the program overnights or during work hours. If you add in the GamePlay hours and Blu-Ray moments, I think the PS3 is going to be running to hot...  :)

Pixelgen
I thought the same thing until I found out they ran Tests at running the PS3 for well over 1400 hours straight with no problems at all. The PS3 will be warm regardless of how long or short you leave it on, just like your PC. :)
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thedarkomen

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#48 thedarkomen
Member since 2007 • 859 Posts
I'm doing this anyway, because I can. No reasons needed.
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Quadrifoglio

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#49 Quadrifoglio
Member since 2006 • 5451 Posts
[QUOTE="BViking78"]Since my PC is 24/7 I don't think I'll have any problems to do the same with my PS3 (my Wii is connected 24/7 too)... Anyway my mother, luckly, survived so it's kinda personal too... :)

My mom had cancer too. She survived, so the first thing that i am going to do when i get my PS3, is getting Folding@Home.
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rebirthofman

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#50 rebirthofman
Member since 2003 • 629 Posts
I havent had anyone with cancer in my family. But my mother suffers from Alheimer's diesease and Diabetes she can barely remember me and my family anymore its truly heart breaking. So I am doing this for her. Anyone who has had a loved one suffer from any illness should do this. If I didn't run this program then I would feel like im cheating my moms. This ones for you.