Your Favorite Single Player Game for Each Console.

And the one you want to try most for whatever system you don't have..

Xbox 360 - Mass Effect

Nintendo - Twilight Princess

and dont have a PS3 but would want Ratchet and Clank

Wii - Super Mario Galaxy

360 - Mass Effect

PS3 - Never played but really want to try MGS4

I'm guessing you mean singleplayer only? In which case;

Xbox 360 ~ Mass Effect

Playstation 3 ~ Uncharted

PC ~ Half-Life 2

I don't care for the Wii at all, so I put the PC in it's place despite the fact it isn't a console.

Wii: Resident Evil 4

360: Fallout 3

PS3: Metal Gear Solid 4

PC: Half Life 2

Uncharted and MGS4

PS3 - MGS4

Xbox 360 - Mass Effect

Wii - The Legend of Zelda: Twilight Princess

Xbox 360- Halo 3

PS3- Ratchet and Clank

Wii- Twilight Princess

PS3 - Metal Gear Solid 4

Wii - Super Smash Bros. Brawl (it's the only game I own)

PC - The Sims 3

PS3 - MGS4

360 - GH

Wii - Madworld

PC - Dawn of War

Wii - Super Mario Galaxy

360 - Bioshock or Prototype

360: Gears of War 2

Wii: Twilight Princess

Xbox 360 - Tales of Vesperia
Nintendo Wii - Legend of Zelda: The Twilight Princess
PS3: Uh...

360 - Dead Space/Mass Effect

PS3: Uncharted 1/inFAMOUS

Wii: Klonoa

PS3 - MGS4

Wii - SMG

PC - Devil May Cry 4

Wii- SMG/Muramasa

360- Gears1/Vesperia

PS3- Assassins Creed/Mirrors Edge

Wii- Super Mario Galaxy
PS3- Metal gear solid 4
360- never finished any games on a 360. unless you count playing titles like mass effect or gears of war on PC...

360: Dead Rising

(Don't have a) Wii, but I really enjoyed Mario Galaxy

Don't have a PS3 either but I'd probably enjoy MGS4 or Infamous.

PS3: Infamous

DS:Pokemon Platinum

PS2: FFXII

Ps3: Uncharted/MGS4/inFamous

Wii: Twilight princess

N64: All of them

Gamecube: Wind Waker / Super mario Sunshine / probably a couple more but i can't think of them right now.

PC: haven't played half life 2 yet.

xbox360-Mass effect

PS3- Valkyria chonicles

PC- Crysis

360 - Orange Box and Dead Space

360 (downloadable) - Braid, Puzzle Quest, and Sam and Max: Save The World

Wii - Twilight Princess and Resident Evil 4: Wii Edition

PS3 - Don't own a PS3 but based on my experience with the past games in the series, it would be Metal Gear Solid 4

PC (only counting games since the launch of 360) - Audiosurf, Supreme Commander, and Oblivion

PC: GTA San Andreas

PS2: God of War

DS: The World Ends With You

PS3 - Demon's Souls

PC - Pool of Radiance : Ruins of Myth Drannor

Xbox 360 - Lost Odyessy

PS3 Metal Gear Solid 4

Wii Super Mario Galaxy

360 - lost odyssey

ps3 - uncharted

wii - super paper mario

PS3: MGS4

360: Mass Effect

PC: Star Wars Republic Commando

Wii- Super Mario Galaxy

360 - Fable II

PS3 - MLB '09 the Show

PC - Heroes of M&M III