While My Sims is a far departure from it's PC counterpart, it is a fairly enjoyable game
Don't go into the game with high expectations that you would have for a proper Sims game, because if you do you'll be disappointed, if you don't then you'll be able to enjoy the game for mindless fun.
You start off by making your Sim, which has no gender. I spent five minutes looking around the create a sim screen for a gender switch option. I figured out that you simply have to cycle through the hair/clothes until you get male/female items and then change your voice. Safe to say, cross dressing can happen a lot in this game, and if you're... freaky, transsexuals can come far too many. Someone call Jack Thompson. Anyways, after that... LOADING SCREEN
Yes, am I wrong to think that I have never actually noticed a loading screen on a Wii game? For all the games I've played I can't seem to remember any game having them. Well My Sims has them every time you enter or exit a building and every time you start building. They are fairly long and common so its quite the annoyance.
But anyways, the premise is, you need to rebuild a town to get people to move in and then interact with them. Building buildings is pretty easy, it's pretty much just using building blocks. Same goes for items and furniture. You will also need to collect "essences" which you can use to paint stuff or add items. These essence items are necessary for objectives such as "Make a chair with 6 sad essences for the whiny emo kid down the street" If you're having a bad day, you're not going to be happy when you have to actually go around and grind the game just to find the essence you need.
Despite it's flaws, My Sims is an enjoyable time passer, but don't think that it is a must have for your Wii collection... unless you're a ten year old who doesn't know better and just likes bright colors.