5-3=2 x 6 = 12

5x3=15+6= 21

3+6=9 x 6=54 + (3x6)=72/6=12

OMG 12/21/12 it's the day that the Mayans predicted the world would end. I think Kojima is trying to tell us that the world is going to end on December 21, 2012!!!!!!!!!!!

Snake!? Snake!? SNAAAAAKKEEEEE!!!!!!!!