For my first time through, MGS3 is pretty fun.
It makes for some good gaming when I am at home during sick days.
Back in 2002 I got Mononucleosis. I remember being so, so tired. I was on bed rest for a week and then was limited to 1/2 days at work for another two weeks to allow for a full recovery. During that time I played a lot of Neverwinter Nights.
Shortly thereafter I got a PS2 and never looked back. Lately I have not been feeling well and have taken the time to play MGS3 when I have not been sleeping. Besides the standard fares, Subsistence has been the staple of my "down" time.
The verdict is still out on the Snake versus Monkey mode. All-in-all the extras have been superb. They were actually the first things my wife and I watched. Now I can play the game and get the full experience.
Tastes like chicken.