I recently got Vista Business up and running on my PC.  I must say that it really does look good.  However, there are a few quirks with it.  First, I had a problem with WoW.  The game ran very jerky like and the sound was skipping.  So I did some research on it and found an answer to my solution.  It turns out that it was as simple as updating my drivers on my video cards.  After that, the game now runs perfect.  Even better than XP ran it.  Its really amazing, I couldn't believe that DirectX 10 would make such a difference.  Still, I have a few problems with it.  The permission stuff is really getting annoying and is completely useless to me.  I mean I can't even sync up my iPod because it says I don't have permission to write to that folder, even though I am the admin.  So doesn't make sense.  Whatever, just keep your drivers updated.  UPDTATE THEM!