Awesome Protagonist (Not in any order of importance.)

Duke Nukem - Duke Nukem series

Sam "Serious" Stone - Serious Samseries

Jake "Nomad" Dunn - Crysis

Master Chief - Halo series

Tequila - Stranglehold

Lara Croft - Tomb Raider series

Tommy - Prey

Max Payne - Max Payne and The Fall of Max Payne

Matthew Kane - Quake 4

Kyle Katarn - Star Wars Jedi Knight Dark Forces II, and Star Wars Jedi Knight II: Jedi Outcast

Gordan Freeman - Half Life series

Marcus Fenix - Gears of War

Sam Fisher - Tom Clancy's Splinter Cell series

Jack Carver - Far Cry

J.C. Denton, Paul Denton, and, Alex Denton - Deus Ex series

John Mullins - Soldier of Fortune I and Soldier of Fortune II : Double Helix

Commander Shepard - Mass Effect series