It can probably be done in multiple discs but it defeats the reason for console exclusives. If you really want to play MGS4 its simple... get a PS3.

DJSAV_101

i own a 360, and i dont really see any reasons to get a PS3 other then MGS4. i already beat the game at my friend's house so im all set :D but i think the 360 is a more fun console. other then the fact that microsoft charges for EVERYTHING with those darn Microsoft Points. its prety good :D