On Pc i would definitely go with Wing Commander or all those D&D Games that where done by SSI(Ravenloft ,Stronghold ,Darksun...).

On Console i would really want to see an old rpg (Lunar,Phantasy star ) or a turn based strategy like the old Shining Forces or Dark Wizard on sega cd.

I also miss Snatcher on sega cd and the old Resident Evil (my apologies to the currents RE fans).

P.S god bless emulators (my 486 and sega cd busted 2 years ago :)