One of the best rpg/adventures I've played in years. The atmosphere, setting, quest lines are top notch.
The combat is more hands on then your usual rpgs, though there are a few problems where you seem to just "not" attack when you click for some reason (read the official boards, many people are having this problem) but it doesn't happen too often for me so it's not a huge deal. There's a ton of skills to learn, I mean you literally have like 5 tier's of skills for every combat stance (six total, 3 for each of your two swords) then 5 tier's for all your signs, then 5 for all your attributes (Sta/dex/int/str). So many to learn and some that sound great too. I went mostly with Dex so far because of the skills that just sounded fitting for the type of character I want to build (IE deflect arrows, higher dodge, etc).
Speaking more of the atmosphere of the game and characters. The game, even though it features dwarves and elves, is told in a much more "realistic/gloomy" matter, not your usual high fantasy stuff. The dwaves/elves are treated as outsiders and "lower class" of humans and racism among other things you will see throughout the game. The characters themselves are brought to life with some overall good voicework (some can be cheesy at times, but not too often) which just goes to show how far a good writer (for the dialogue) and voice actor can take a game that much further. Some models are used over and you will notice "clones," even sometimes standing right beside each other. However after you get into the game this won't be an eyesore really as the characters you converse with and talk to are generally very well done.
The world itself has a more late middle-ages Germanic countryside feel to it. Some great time of day effects that are not only cosmetic but actually affect things in the world, such as monsters that only appear at night or when it's raining as well as npc's seeking cover from rain.
The world itself is filled with more mature things that rpg's have been lacking since games like Fallout/Daggerfall/Baldur's gate left the scene. You'll encounter the things you'd expect, Violence, sex, coarse language among more importantly, the storylines and context of the world and characters.
I have only a few minor gripes in the whole so far. The lack of a screenshot button (have to use fraps or alt-tab) and no ability to hide the hud that I can find are a bit annoying, especially because of some of the beautiful scenes and environments you'll see exploring the world. For some reason the cutscenes sometimes lag. At first they were doing really really bad lag, but I turned off Depth of Field (which is only used in cutscenes) and put things to medium and now it runs fine for the most part. The loading in and out is the biggest hit to the game. Having to load a small hut going in, then turning around after just a few seconds inside to have to reload the exterior cell can take a while, and if you like to explore every nook and cranny in rpgs as I do, it will annoy you from time to time.
In closing, even with the loading problems and other ones they are dwarfed by how fun and great the game as a whole is. This is one of the best rpg's I've played in some time and I hope it won't be the last from CD Projekt.