Short but incredibly fun.
Story/Gameplay: Really cheezy, anime storyline. Not much to say about that. A weird virus/parasite thing called GUILT gets spread throughout the world and you have to stop it using your surgical skills. The storyline's pretty bad but it's easy to ignore it just from how fun the game itself is.
You start out as a rookie doctor who is just ending his internship. You have to remove glass from a motorcycle crash victim and from there, you're set off into a chapter-based surgical journey. The tutorials set you up really well and don't last very long so you're off on your own pretty soon. You use the wii numchuck attachment to select your surgical tool by moving the joystick in the direction associated with the tool you want. You then use the wii-mote to aim your tool and press the A button to use. Very simple but there are a lot of factors that complicate this game. Your patient is constantly dropping in vitals due to various injuries/diseases that you have to cure. You must cure the person of their ailment while making sure to keep their vitals above zero or you lose. Add into that a 5 minute time limit and you've gotta be extremely careful and quick. The level of difficulty is a little high but due to the five minute limit, you aren't usually replaying that much if you lose. The game ends relatively soon but with a bonus X chapter that comes after you beat the game that is absurdly difficult, you won't get bored too quickly.
Graphics: The graphics are pretty poor but it doesn't detract too much from the game. The injuries are all pretty much the same looking and are basically just the same cut or tumor over and over again. Also, the organs look horribly unrealistic. The anime graphics outside of the gameplay look refreshing though and add a touch of color and happiness into the game.
Sounds: The voice-overs are sparsly repeated lines but they sound pretty good. They do a good job of saying their overly dramatic lines. The music is also not bad, especially the last mission music. It adds a sense of calm that helps you stay steady during normal missions but the last battle one gives an extreme tension that is almost an obsticle in itself. This isn't a bad thing though since it just makes it feel all the better once you win.
Value: As I said above, it's a relatively short game but a hard one. If you are an average gamer, you should finish this in about 20 hours including side missions. Due to the cost, i recommend this as a rental.