ATX vs Micro-ATX

Are there any significant differences between a Micro ATX motherboard and just a standard ATX?

Specifically, these motherboards here:

ATX

Micro ATX

Only 1 PCI-E connector, so you can't run other devices that require a PCI-E slot.

Can't really say that the PCI-E 1x on the motherboard is good for anything because it's right there next to the heat sink will could cause interference for most pci-e 1x cards.

If you have a mid-tower case I don't really see the point in getting a micro ATX motherboard.

Well what I think is that MATX is like for small rooms and atx for mid sized rooms like for me I got a small bedroom and I'm gonna switch to a matx htpc gaming rig case so I can put my PC on my desk and get more space out of my bed room since my cosmos 1000 takes up sooo much room its not even funny. Hekynn