Raid 0 simple question

I think you can set up any hard drive in raid 0 even if the hdds are diff sizes but is that the best idea? Would they be most likly to crash if one is 320gb and one is 160gb? I know you will loose 160gbs from the 320 but that does not matter. Im asking if different size and model will effect the life of a raid 0 configuration. Thank you!

^^^ What he said

Raid drives have to be limited in size and speed by the smallest and slowest drive in the array.