The GTA logo has a spade in the V

You know from a deck of cards. I think this probably means Los Venturas given the money symboling as well. Could be wrong but I'm not sure if anyone else has noticed the spade in the V

ok I see it now.

might be the green from ireland as well and boston, a gta game in a boondock saints setting. but probably more than just a city. oerhaps different states and city to travel too

gta 4, san andreas, vice city and maybe some new combined _O_

I always love the speculation about the location of the new GTAs :P

Kotaku says it's set in LA, featuring multiple playable characters:

http://kotaku.com/5853279/grand-theft-auto-v-will-be-set-in-los-angeles-may-star-multiple-characters